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With respect to ethnic-ity in the group with SLI, 34 of the childrenwere White, 3 were Hispanic, 2 were Asian,2 were African American, and 2 were of mixed-race background With respect to ethnic-ity in the group with SLI, 34 of the childrenwere White, 3 were Hispanic, 2 were Asian,2 were African American, and 2 were of mixed-race background. TGF-? signaling in aortic aneurysm: another round of controversy.J Genet Genomics. often the top concentration evaluated showed asignificant reduction in the number of cells that wereviable enough to reach metaphase often the top concentration evaluated showed asignificant reduction in the number of cells that wereviable enough to reach metaphase. Mdm2localization in MCF-7 cells switches from being almost exclusively cytoplasmic tonuclear under virtually anoxic conditions, without a change in the level of Mdm2.Interestingly, this translocation of Mdm2 is blocked by geldanamycin, an inhibitorof Hsp90 required for HIF1? stabilization [ 51]. 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